Researchers working on COVID-19 therapy with plasma from convalescent patients have found that it is safe and effective and improves the chances of survival among those who are severely ill. The new study titled, “Safety Update: COVID-19 Convalescent Plasma in 20,000 Hospitalized Patients,” is published as a preprint for the journal Mayo Clinic Proceedings. What
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The drug hydroxychloroquine, pushed by U.S. President Donald Trump and others in recent months as a possible treatment to people infected with the coronavirus disease (COVID-19), is displayed at the Rock Canyon Pharmacy in Provo, Utah, May 27, 2020. George Frey | Reuters The National Institutes of Health has halted its clinical trial of the anti-malaria drug hydroxychloroquine
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Reviewed by Emily Henderson, B.Sc.Jun 18 2020 Social distancing and limited access to contraceptive and abortion care during the COVID-19 pandemic is affecting the sexual and reproductive health of adolescents and young adults according to a new study by researchers at Columbia University Mailman School of Public Health and Rutgers University. The researchers address how
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It hurts when I run. That’s what many orthopedic surgeons hear when runners and other athletes come into their offices. Sometimes people have obvious problems, such as strains or sprains. Other times these issues can be tricky to diagnose. The runner you’re about to meet had symptoms he thought were no big deal. But he
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Reviewed by Emily Henderson, B.Sc.Jun 19 2020 A new study finds that clinicians can use patient data, such as a history of co-occurring health conditions and medication, to predict the 5- and 10-year life expectancy of older people with diabetes. The ability to make such predictions, the researchers say, may help clinicians and patients develop
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Neuroblastoma is one of the most common cancers in children and has limited treatment options. In a new study, researchers from Kanazawa University retrospectively analyzed children with refractory or relapsed high-risk neuroblastoma who were treated with 131I-metaiodobenzylguanidine (131I-MIBG) and discovered a favorable prognosis in these patients. Neuroblastoma forms in organs that embryologically originate from nerve
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As cases continue to surge throughout the American South and West, some state officials are rethinking how to reopen. Arizona Gov. Doug Ducey on Wednesday reversed his stance against mandating mask wearing and allowed local officials to set their own regulations. Oregon Gov. Kate Brown announced Wednesday that most of the population will have to
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Reviewed by Emily Henderson, B.Sc.Jun 17 2020 A new test developed at CHU Sainte-Justine in Montreal will enable better management of patients with severe combined immunodeficiency (SCID). The results of this work was presented Tuesday in the medical journal Blood Advances published by the American Society of Hematology. Routine neonatal screening, although not yet available
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The development of a subtype of inflammatory myopathy characterized by interstitial lung disease and positivity for a specific autoantibody was influenced by seasonality and place of residence, Japanese researchers found. Among patients with polymyositis or dermatomyositis (PM/DM) and the associated interstitial lung disease, symptom onset occurred most often from October to March for those with
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Reviewed by Emily Henderson, B.Sc.Jun 16 2020 In research led by a University at Buffalo pediatric endocrinologist, a drug called golimumab showed that it preserved beta-cell function in children and young adults with newly diagnosed Type 1 diabetes, according to findings from a Phase 2 study. The study also demonstrated that golimumab, an anti-tumor-necrosis-factor (TNF)
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Reviewed by Emily Henderson, B.Sc.Jun 16 2020 A research team led by Dr Chaogu Zheng from the School of Biological Sciences at the University of Hong Kong (HKU), in collaboration with a team led by Professor Martin Chalfie (2008 Nobel Laureate in Chemistry) from the Department of Biological Sciences at Columbia University, recently discovered an
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Cleveland Clinic researchers have developed the world’s first risk prediction model for healthcare providers to forecast an individual patient’s likelihood of testing positive for COVID-19 as well as their outcomes from the disease. According a new study published in CHEST, the risk prediction model (called a nomogram) shows the relevance of age, race, gender, socioeconomic
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The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that is causing the COVID-19 pandemic across the world has undergone a genetic mutation in the density of functional spikes on the virus, says a new study. This has led the virus to become highly infectious and easily transmissible between humans. The study from Scripps Research is
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New coronavirus cases and hospitalizations continue to rise in a handful of U.S. states, prompting warnings from some health officials that greater precautions might be necessary to keep the health systems from being overwhelmed. As people grow fatigued from social distancing and other precautions, pharmaceutical and biotech companies are racing forward to develop treatments and
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A new German study published on the preprint server bioRxiv* in June 2020 shows that the drug remdesivir can reduce the replication of SARS-CoV-2 in human intestinal organoids. Gut Symptoms of COVID-19 The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which led to the COVID-19 pandemic causes mostly mild or asymptomatic disease. Still, up to
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With multiple drugmakers in a push for a Covid-19 vaccine, countries are preparing for when it is finally available and putting deals in place with companies to prepare for the eventual distribution. AstraZeneca, which has a vaccine under development at Oxford and is expected to complete the experimental phase by the fall, agreed to deals with
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With the epidemic of burnout amongst doctors and the majority not recommending medicine to their children, how can you know whether or not you would be happy as a future physician? Here’s how to find out. 💌 Sign up for my weekly newsletter – https://medschoolinsiders.com/newsletter 🌍 Website & blog – https://medschoolinsiders.com 📸 Instagram – https://instagram.com/medschoolinsiders
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Reviewed by Emily Henderson, B.Sc.Jun 12 2020 Scientists at RCSI University of Medicine and Health Sciences have developed a new biomaterial that has the potential to accelerate bone regeneration by promoting an immune response that encourages repair and lowers the risk of inflammation. The study, conducted by researchers at RCSI Tissue Engineering Research Group (TERG)
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