Clinical Trials & Research

India faces a global health crisis as the number of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections reaches over 23.7 million. As the country’s health system buckles with increased admissions and a lack of resources, another health threat has emerged. Public health officials report a rare black fungus infection, called mucormycosis, which is increasingly
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insights from industryGermano TarantinoScientific DirectorPharmaNutra S.p.A In this interview, Germano Tarantino, the Scientific Director at PharmaNutra S.p.A, talks to NewsMed about long-COVID (also known as chronic COVID syndrome). To begin, can you tell us a bit about chronic COVID syndrome (also known as Long-COVID) and some of its symptoms? Long-COVID is a syndrome characterized by
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Ziath offer a complete OEM design, development and supply service based upon its extensive experience of creating high performance 2D barcoded tube scanners and rack readers for biobanking, compound library, pathology and COVID-19 sample management applications. Over the last 15 years – Ziath has established itself as a leading international manufacturer and supplier of instruments
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Countries like the UK, Israel, and the USA are now in the thick of successful vaccine campaigns against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the COVID-19 pandemic. As the vaccine rollout continues, there have been thousands of anecdotal reports of receivers suffering symptoms of mild fatigue, achiness, and fever in
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St. Jude Children’s Research Hospital scientists have developed an integrated, high-throughput system to better understand and possibly manipulate gene expression for treatment of disorders such as sickle cell disease and beta thalassemia. The research appears today in the journal Nature Genetics. Researchers used the system to identify dozens of DNA regulatory elements that act together
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May 6 2021 A global conference on human fertility has been warned of huge societal and ethical challenges regulating advances in gene editing in assisted reproduction. Speaking at the 10th Congress of the Asian Pacific Initiative of Reproduction (ASPIRE), Dr Catherine Racowsky said embryo gene editing was a growing likelihood among latest advances in IVF
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Thought LeadersDr. Samantha WalkerDirector of Research & InnovationAsthma UK and the British Lung Foundation In light of World Asthma Day, News-Medical interviewed Dr. Samantha Walker from Asthma UK and the British Lung Foundation about some of the common misconceptions surrounding asthma. Please could you introduce yourself and tell us about your expertise in asthma? My
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Social media may make it easier for people to engage online, but it does not provide certain benefits of real-life human interactions, says a Michigan State University researcher. Problematic social media use has been associated with depression, anxiety and social isolation, and having a good social support system helps insulate people from negative mental health.
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Scientists have known for a while that SARS-CoV-2’s distinctive “spike” proteins help the virus infect its host by latching on to healthy cells. Now, a major new study shows that they also play a key role in the disease itself. The paper, published on April 30, 2021, in Circulation Research, also shows conclusively that COVID-19
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Histology is the study of biological tissues at a microscopic level. Also called microscopic anatomy, histology is widely used to provide diagnosis of cancer and other diseases. For example, tissue samples obtained during surgery might help to determine whether further surgical action is needed, and further surgery may be avoided if a diagnosis can be
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Changi General Hospital (CGH) and the Singapore University of Technology and Design (SUTD) have developed the Blood WArning Technology with Continuous Haemoglobin (BWATCH) sensor, a lightweight monitoring device placed over a patient’s bandage that detects real-time bleeding from wound sites following invasive medical procedures. BWATCH was tested and validated in an observational clinical trial involving
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Apr 30 2021 Researchers from the University of Eastern Finland and the University of Oulu in collaboration with an international team have created a new diagnostic biomarker-based algorithm for the diagnostics of dementia. The team is led by Professor Barbara Borroni from the University of Brescia, Italy. The article was published in the Diagnostics journal.
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D-CLIP, a lifestyle education program to prevent diabetes in South Asians with prediabetes, increased moderate-to-vigorous intensity physical activity (MVPA) by up to nearly an hour a week, researchers at the Rush Institute for Healthy Aging have found. The results of their study were published online Feb. 28 in the medical journal Diabetes Research and Clinical
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CHARGE syndrome is a rare genetic disorder affecting about 1 in 10,000 newborns. It can lead to neurological and behavioural disorders for which no treatment is currently available. Dr. Kessen Patten and his team, from the Institut national de la recherche scientifique (INRS) have just discovered a compound that could alleviate these symptoms. The results
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Apr 27 2021 A national study of 20,000 patients conducted by RCSI University of Medicine and Health Sciences and the HSE Health Protection Surveillance Centre (HPSC) has identified the underlying conditions that are associated with more severe outcomes from COVID-19 in an Irish setting.   The research, which has been published in The Lancet Regional
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Thought LeadersDr. Laurence SlutskerSenior Technical AdvisorMalaria and Neglected Tropical Diseases, PATH In support of World Malaria Day, News-Medical spoke to Dr. Laurence Slutsker, an internationally recognized expert in malaria, about fighting this disease in 2021. Please can you introduce yourself and tell us about your career in research into malaria and neglected tropical diseases (NTDs)?
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Can a high dose of vitamin D administered on admission to hospital improve the condition of patients with moderate or severe COVID-19? The answer is no, according to a Brazilian study published in the Journal of the American Medical Association (JAMA). The article reports a randomized, double-blind, placebo-controlled clinical trial, the kind of study considered
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The Native Antigen Company, part of LGC Clinical Diagnostics and one of the world’s leading suppliers of reagents that enables research into diagnostics and vaccines for emerging and endemic infectious diseases, today announced the launch of its SARS-CoV-2 Neutralisation Assay Development Kit. The kit can be used to identify and qualitatively assess the ability of
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Apr 22 2021 A team of scientists from Russia studied the role of double-stranded fragments of the maturing RNA and showed that the interaction between distant parts of the RNA can regulate gene expression. The research was published in Nature Communications. At school, we learn that DNA is double-stranded and RNA is single-stranded, but that
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Listening to music before going to be can improve sleep quality among older adults, according to an analysis of all relevant published clinical trials. In the analysis, which is published in the Journal of the American Geriatrics Society, five randomized trials met the investigators’ criteria. Older adults who listened to music experienced significantly better sleep
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Apr 19 2021 Varying severity of COVID-19 symptoms in patients is reflected by levels of a chemical biomarker in their body which scientists say could be used to better manage treatments and other interventions, including vaccinations. In a new paper in International Journal of Infectious Diseases, medical experts in Italy and Australia examined levels of
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Today, the U.S. Food and Drug Administration revoked the emergency use authorization (EUA) that allowed for the investigational monoclonal antibody therapy bamlanivimab, when administered alone, to be used for the treatment of mild-to-moderate COVID-19 in adults and certain pediatric patients. Based on its ongoing analysis of emerging scientific data, specifically the sustained increase of SARS-CoV-2
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Today, the U.S. Food and Drug Administration approved Opdivo (nivolumab), in combination with certain types of chemotherapy, for the initial treatment of patients with advanced or metastatic gastric cancer, gastroesophageal junction cancer and esophageal adenocarcinoma. This is the first FDA-approved immunotherapy for the first-line treatment of gastric cancer. Today’s approval is the first treatment in
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People who have recovered from COVID-19 had a robust antibody response after the first mRNA vaccine dose, but little immune benefit after the second dose, according to new research from the Penn Institute of Immunology. The findings, published today in Science Immunology, suggest only a single vaccine dose may be needed to produce a sufficient
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