Allergies & Asthma

Inhaled budesonide (Pulmicort), a steroid generally used to treat asthma, dramatically reduced the need for hospitalization in COVID-19 patients within a week of symptom onset, a small randomized trial in the U.K. found. Among 139 patients with mild COVID-19 symptoms, 10 in the control group required either a COVID-19-related urgent care or emergency department (ED)
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Barbecue can return to the menu for individuals with “alpha-gal” syndrome — severe allergic reactions to the alpha-galactose saccharide found in red meat — with FDA approval Monday of pigs engineered to lack an enzyme considered key to the condition. Developed by a company called Revivicor, the “GalSafe” pigs might also have therapeutic potential as
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It’s no secret that there’s a lot of wasteful spending in healthcare, and patients have become increasingly frustrated by this as their insurance premiums have skyrocketed. Yet unnecessary procedures are still performed every day in the U.S. — and sometimes patients are harmed as a result. MedPage Today‘s Enterprise & Investigative Reporting team needs your
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New therapies and devices for chronic obstructive pulmonary disease (COPD) were approved in 2020 and researchers continued to explore expanding the definition of disease beyond spirometry. But 2020 was dominated by the struggles managing the care of highly vulnerable COPD patients during the COVID-19 pandemic. COVID Paradox The delivery of routine components of COPD care,
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“While doctors have long believed that dementia presents in the checkbook, our study helps show that these financial symptoms are common and span years before and after diagnosis.” — Lauren Hersch Nicholas, PhD, MPP, of Johns Hopkins University in Baltimore, on research showing difficulties with finances were evident long before dementia diagnosis. “Hospitals, they want
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New guidelines from the National Asthma Education and Prevention Program (NAEPP) of the National Heart, Lung, and Blood Institute (NHLBI) — the agency’s first update since 2007 — take account of new management options including single maintenance and reliever therapy (SMART) and long-acting muscarinic antagonists (LAMAs). As has long been standard practice, the foundation for
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Note that some links may require registration or subscription. Pfizer and BioNTech announced emergency authorization from the United Kingdom for their COVID-19 vaccine on Wednesday. Meanwhile, White House Chief of Staff Mark Meadows invited FDA Commissioner Stephen Hahn, MD, to come explain why his agency hasn’t yet granted an emergency use authorization (EUA) for Pfizer’s
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Omalizumab (Xolair) maintained efficacy for chronic rhinosinusitis with nasal polyps, a researcher reported. In an open-label extension study of two, 24-week clinical trials, omalizumab was associated with significant improvements in nasal polyp scores (mean change -0.97, 95% CI -1.25 to -0.69), nasal congestion scores (mean change -0.99, 95% CI -1.14 to -0.83), and Sino-Nasal Outcome
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Owning a dog while pregnant appeared to shape children’s immune systems well into adolescence, a researcher reported. In a cohort of 1,193 mother-child pairs in southeast Michigan, the area under the curve for immunoglobulin E levels over ages 10-14 (“IgE trajectory”) was 28.8% lower in children with prenatal pet exposure vs children whose mothers kept
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Treatment with the investigational anti-IgE biologic ligelizumab was generally effective in patients with H1 antihistamine-unresponsive chronic spontaneous urticaria (CSU) who did not achieve complete symptom control with omalizumab (Xolair), an exploratory analysis of a phase IIb extension study showed. In a subset of omalizumab-treated patients with a score greater than 0 on the 7-day urticaria
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The investigational monoclonal antibody tezepelumab proved to be an effective therapy for uncontrolled severe asthma in patients with and without perennial and seasonal allergies, a post-hoc analysis of data from the phase II PATHWAY study found. The subgroup analysis focused on patients who did and did not have baseline sensitivity to perennial allergens such as
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Results from a preliminary study showed novel voice and breath analysis using a smartphone app to be a useful measure of lung function, and researchers say the technique may prove to be a valuable tool for identifying and monitoring respiratory disease. Automated voice and breath analysis was found to have value for predicting lung function,
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Patients with cancer and COVID-19 have a higher risk of severe disease and mortality, researchers reported. Of 89 cancer patients admitted to the intensive care unit (ICU) due to COVID-19, 32 died, a mortality rate of 36%, reported Michael Dang, MD, a critical care fellow at Memorial Sloan Kettering Cancer Center in New York City,
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Patients diagnosed with chronic obstructive pulmonary disease (COPD) who reported using marijuana had less risk of in-hospital mortality and pneumonia than non-users, according to a nationwide population-based study. Use of marijuana was associated with a 37.6% reduction in the odds of dying in the hospital (OR 0.624, 95% CI 0.407-0.958, P=0.0309) among patients diagnosed with
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