In recognition of the importance of this technology to the future of biomedical research, a consortium formed by HMS, Harvard University’s Office of the Provost, Boston Children’s Hospital, the Dana-Farber Cancer Institute and Massachusetts General Hospital established the Harvard Cryo-EM Center for Structural Biology, which makes access to cryo-EM broadly available to the Harvard research
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As the world struggles with the coronavirus pandemic, more and more people are trying to protect themselves against the virus by all means possible. There are currently no vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), so boosting the immune system by way of diet, regular exercise, and sleep are sensible measures. It’s essential
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Reviewed by Emily Henderson, B.Sc.Mar 30 2020 New findings from researchers at The University of Texas MD Anderson Cancer Center about how some cancer cells become “addicted” to glucose could open up fresh approaches to therapy strategies for cancers with high levels of an amino acid transporter called solute carrier family 7 member 11 (SLC7A11).
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Reviewed by Emily Henderson, B.Sc.Mar 27 2020 Though many negative repercussions of human immunodeficiency virus infection can be mitigated with the use of antiretroviral therapy (ART), one area where medical advances haven’t made as much progress is in the reduction of cognitive impacts. Half of HIV patients have HIV-associated neurocognitive disorders (HAND), which can manifest
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Reviewed by Emily Henderson, B.Sc.Mar 27 2020 Oncotarget Volume 11, Issue 12 reported outside its natural niche, the cultured prostate cancer stem cells lost their tumor-inducing capability and stem cell marker expression after approximately 8 transfers at a 1:3 split ratio. To characterize the iPS87 cell line, cells were stained with antibodies to various markers
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Reviewed by Emily Henderson, B.Sc.Mar 27 2020 Allison Jack, Assistant Professor, Psychology, is examining gene coexpression and brain connectivity in females with autism spectrum disorder (ASD). To do this, Jack is conducting a secondary analysis of de-identified data from a National Database for Autism Research collection called “Multimodal Developmental Neurogenetics of Females with Autism.” During
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Reviewed by Emily Henderson, B.Sc.Mar 27 2020 UC Davis Health has two clinical trials underway for hospitalized patients with severe COVID-19, the disease caused by the novel coronavirus, SARS-CoV-2. The studies are evaluating the safety and effectiveness of two drugs — the investigational antiviral remdesivir, and sarilumab, a drug that blocks the body’s acute inflammatory
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Researchers from Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China have looked at the outcomes of pregnant mothers with COVID-19 and their newborns. Their study titled, “Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-center, descriptive study” was published in the latest
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Reviewed by Emily Henderson, B.Sc.Mar 26 2020 Geographically isolated from mainland Eurasia, the island nation of Japan has seen little in the way of population mixing for thousands of years. In fact, after two waves of human migration–one 40,000 years ago from Southeast Asia and one 3,000 years ago from the Korean Peninsula–Japanese people are
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Reviewed by Emily Henderson, B.Sc.Mar 25 2020 Novel, fully digital, high-resolution positron emission tomography/computed tomography (PET/CT) imaging of small brain stem nuclei can provide clinicians with valuable information concerning the auditory pathway in patients with hearing impairment, according to a new study published in the March issue of The Journal of Nuclear Medicine. Using 18F-FDG
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Poor diet is a significant contributor to chronic diseases, including cardiovascular disease, cancer, obesity, and diabetes accounting for early mortality. A new study published in the journal JAMA in March 2020 shows that dietary deficiency is both prevalent and pathogenic in today’s young America. Factors that affect diet quality include what children are fed when
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Reviewed by Emily Henderson, B.Sc.Mar 24 2020 Since the discovery of penicillin in 1928 by Sir Alexander Fleming, antibiotics have saved millions of lives from fatal infections world-wide. However, with time bacteria have developed mechanisms to escape the effects of antibiotics – they have become resistant. With fewer antibiotics available to treat resistant bacterial infections,
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Hereditary angioedema (HAE) is one of the more puzzling phenomena in immunology, in part because, even though it’s an autoimmune disease involving complement dysregulation, it’s generally treated by allergists because its symptoms impersonate those of severe allergic reactions. At the American Academy of Allergy, Asthma, and Immunology’s annual meeting — cancelled because of concerns surrounding
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This is a live blog. Please check back for updates. Global cases: At least 334,981, according to the latest figures from the World Health Organization Global deaths: At least 14,652, according to the latest figures from the WHO All times below are in Beijing time. 8:54 am: Washington state Gov. Jay Inslee issues stay-at-home order  The state
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